Comparison Guide

Avanan vs Mimecast

Avanan and Mimecast both protect business email, but use fundamentally different architectures. Mimecast is a traditional Secure Email Gateway, while Avanan uses API-based inline scanning for deeper M365 integration.

Last updated

Quick Answer

Mimecast wins for most buyers.

More effective for M365 with API-based inline scanning.

Side-by-Side Comparison

Feature Avanan Mimecast
Architecture API-based inline scanning Secure Email Gateway (SEG)
MX Record Change Not required Required
Internal Email Scanning Yes No (inbound only)
Email Archiving Via M365 retention Built-in archiving
Email Continuity Via M365 redundancy Built-in continuity
Incident Response CIRT available (add-on) Not included

Our Verdict

Avanan provides better protection for Microsoft 365 environments through API integration that catches internal threats and BEC attacks that traditional gateways miss. Mimecast remains a solid choice for organizations needing email archiving and continuity features.

Unio Digital recommends: More effective for M365 with API-based inline scanning

Quick Picks

Which one should you pick?

Three buyer profiles, three answers. Pick the row that fits.

Microsoft 365 SMB / mid-market

Pick: Avanan

Your mail lives in M365 and you want API-based inline scanning that also inspects internal email and catches BEC, deployed in minutes with no MX cutover or mail flow risk.

Get an Avanan quote

Archiving and continuity requirements

Pick: Mimecast

You need built-in email archiving for e-discovery or compliance, plus continuity that keeps mail flowing if Exchange Online goes down. A gateway vendor operating since 2003 with 42,000+ organizations fits that brief.

Talk to a strategist

In-house IT, licensing and setup only

Pick: Either platform

Unio can license either tool, handle the API or MX onboarding, and tune policies, then hand day-to-day triage to your internal team. You keep the console, we do the rollout.

Scope a licensing quote

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Frequently Asked Questions

For M365-centric environments, Avanan provides better threat detection through API integration. Choose Mimecast if you need built-in email archiving and continuity features beyond what M365 provides.

Learn More About Email Security

Visit our comprehensive Email Security page for detailed information about our capabilities and approach.

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Sources & Methodology  

Specifications, pricing, and product capabilities cited on this page are sourced from public vendor documentation as of the dates shown below. Vendor product lines change quickly; verify current specs and pricing directly with each vendor before purchasing.

  1. Check Point Harmony Email and Collaboration advertises 99.7% phishing prevention and 99.9% malware prevention across 65,000+ customers, with API connection in minutes. [source] · verified 2026-07-01
  2. Avanan was acquired by Check Point Software in 2021 and ranked 125th on the 2021 Deloitte Technology Fast 500, up from 171st in 2020, as one of the fastest-growing email security companies in North America. [source] · verified 2026-07-01
  3. Check Point's Harmony Email and Collaboration admin guide documents threat detection policies for internal emails: internal traffic is inspected in Detect and Remediate mode by default, with an optional Protect (Inline) mode that scans internal mail before delivery. [source] · verified 2026-07-01
  4. Mimecast's flagship email security deployment is an MX-based secure gateway where all incoming mail routes through Mimecast first, intercepting threats inline before delivery. [source] · verified 2026-07-01
  5. Mimecast protects and supports 42,000+ organizations globally and has operated in email security since 2003. [source] · verified 2026-07-01
  6. The FBI IC3 recorded 305,033 domestic and international business email compromise incidents totaling $55.5 billion in exposed losses between October 2013 and December 2023, with a 9% increase in identified global exposed losses from December 2022 to December 2023. [source] · verified 2026-07-01